Efficacy of 308-nm excimer light in the treatment of stable vitiligo

VernacularTitle:308nm准分子激光治疗稳定期白癜风的疗效观察
Author: Rui YIN ; Jun DENG ; Xichuan YANG ; Cunjian ZHOU ; Fei HAO ; Lin LIN ; Yan XIAO
Publication Type:Journal Article
From: Chinese Journal of Dermatology 2011;44(8):594-595
CountryChina
Language:Chinese
Abstract: Objective To evaluate the efficacy and safety of 308-nm excimer light in the treatment of stable vitiligo. Methods Thirty patients with stable vitiligo were enrolled in this clinical trial. All the subjects received the treatment with 308-nm excimer light on a twice-weekly schedule for 3 months. Results The repigmentation rate was 95.0%, 75.0% and 66.7% for lesions in the face and neck, trunk and limbs, with the treatment sessions averaging 10.22 ± 1.60, 19.10 ± 2.38, 37.74 ± 3.06, respectively, and accumulative irradiation dose averaging 7.50 ± 3.45, 10.60 ± 1.01, 18.56 ± 3.05 J/cm2 respectively. Significant differences were observed in the repigmentation rate and treatment sessions between the lesions in the face and neck, trunk and limbs (all P ＜ 0.05). No severe side effects were seen during the treatment. Conclusion 308-nm excimer light is effective and safe for the treatment of vitiligo.