Detection of causative allergens of cosmetic allergic contact dermatitis

VernacularTitle:化妆品变应性接触性皮炎变应原检测分析
Author: Yonglian CAI ; Runqiu LIU ; Xin SHI ; Jing ZHANG ; Ping LI
Publication Type:Journal Article
From: Chinese Journal of Dermatology 2011;44(8):586-589
CountryChina
Language:Chinese
Abstract: Objective To make a survey on common cosmetic allergens, and to provide epidemiological data and clinical evidence for cosmetic allergy. Methods Patch test was performed by using 49cosmetic allergens from a European cosmetic series and 5 Chinese standard screening allergens on 89patients with suspected cosmetic allergic contact dermatitis. Test results were determined according to the International Contact Dermatitis Research Group (ICDRG) recommendation. Results Of the 89 patients, 61(68.5%) showed positive reactions to one or more cosmetic allergens. The most common allergens were fragrances (33.7%), followed by preservatives (30.3%), para-phenylenediamine (25.8%) and amerchol L 101(10.1%). Conclusion Fragrances, preservatives, para-phenylenediamine and amerchol L 101 are dominant causative allergens in patients with cosmetic allergic contact dermatitis.