Comparison of several early drug interventions in postmenopausal women with osteopenia

VernacularTitle:几种治疗绝经后妇女骨量减少干预方案疗效及安全性的比较
Author: Li YOU ; Zhengyan SHENG ; Junming DAI ; Jinyu CHEN ; Ling PAN ; Lin CHEN ; Shizhong WANG ; Heng WU ; Chen JI ; Jian ZHOU ; Yongde PENG
Publication Type:Journal Article
Keywords: Osteopenia; Bone mineral density; Osteoporosis,postmenopausal
From: Chinese Journal of Endocrinology and Metabolism 2011;27(6):502-504
CountryChina
Language:Chinese
Abstract: Two hundreds postmenopausal women with osteopenia, aged 45-80, were randomly divided into 4 groups, and received different drug interventions. After treatment for 12 months, the lumbar spine bone mineral density(BMD)and total hip BMD in alendronate group increased significantly(3.5% and 2.6%, both P＜0.05), the lumbar spine BMD raised 2.0% in selective estrogen receptor regulator group(P＜0.05). Bone turnover indices improved in both groups(all P＜0.05). No change in BMD or bone turnover indices was found in patients treated with active vitamin D3and calcium.