Clinical efficacy of low-dose methimazole therapy in patients with subclinical hyperthyroidism complicated by paroxysmal atrial fibrillation
10.3760/cma.j.issn.1000-6699.2010.11.017
- VernacularTitle:小剂量甲巯咪唑治疗亚临床甲状腺功能亢进症合并阵发性房颤的临床观察
- Author:
Fuman DU
;
Yuzhi YANG
;
Weimin WANG
;
Kun FENG
;
Dan WANG
- Publication Type:Journal Article
- Keywords:
Hyperthyroidism,subclinical;
Atrial fibrillation;
Methimazole
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(5):420-421
- CountryChina
- Language:Chinese
-
Abstract:
Twenty-seven patients with subclinical hyperthyroidism(SH)complicated by paroxysmal atrial fibrillation(PAF)were treated with methimazole plus bisoprolol.All patients were examined by Doppler echocardiogram and 24 h ambulatory electrocardiograms before and 3 months after treatment.Serum FT3,FT4,and TSH levels were measured with RIA.The results showed that low-dose methimazole therapy could improve the left ventricular diastolic function(P < 0.01)and help maintain sinus rhythm.The incidence of subclinical hypothyroidism was low.Low-dose methimazole was effective and safe in patients with SH complicated by PAF.
