HbA1C for diagnosing diabetes:past,present,and future
10.3760/cma.j.issn.1000-6699.2011.05.002
- VernacularTitle:糖化血红蛋白在诊断糖尿病中的意义——过去、现在和未来
- Author:
Yuqian BAO
;
Weiping JIA
- Publication Type:Journal Article
- Keywords:
HbA1C;
Diabetes mellitus
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(5):367-370
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes mellitus is a chronic metabolic disease with complications associated with long-term damage,dysfunction,and failure of various organs,and has become one of the leading causes of impairment of human health.At present,the prevalence of diabetes mellitus reaches 9.7%in China,which is considered one of the countries in the world with heavy diabetes burden.Patients with established diabetic complications will be at higher risk of poor health outcomes and with higsh healthcare costs.These realities support the critical need to identify diabetes and its precursors more efficiently and earlier.The current diagnostic criteria,fasting plasma glucose(FPG),and oral glucose tolerance test(OGYT),that require fasting and multiple blood samplings,may not be acceptable to patients and may limit the clinical application so as to impede the effort to diagnose diabetes in timely fashion.HbA1C,which accurately reflects longer term glycaemia,Can be done at any time without fasting or other preparation of the patient and may not be affected by short term lifestyle changes.Given the recognized need,some panels have been considering the possible utility of HbA1C as a supplementary screening tool to make the diagnosis of diabetes efficiently.
