Effect of intraoperative wake-up test on postoperative delirium in patients undergoing scoliosis surgery under analgesia with sufentanil
10.3760/cma.j.issn.0254-1416.2011.05.012
- VernacularTitle:术中唤醒试验对舒芬太尼镇痛下脊柱侧弯矫形术患者术后谵妄的影响
- Author:
Weiqing MA
;
Chenghua ZHANG
;
Zhigui LI
;
Qi LI
;
Tao YU
;
Wanfeng LI
;
Zhangxiang HUANG
- Publication Type:Journal Article
- Keywords:
Sufentanil;
Postoperative complications;
Delirium;
Scoliosis;
Wake-up tests
- From:
Chinese Journal of Anesthesiology
2011;31(5):560-562
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of the intraoperative wake-up test on the postoperative delirium in patients undergoing scoliosis operation under analgesia with sufentanil. Methods Sixty ASA Ⅰ or Ⅱ patients , aged 12-60 yr, scheduled for scoliosis surgery, were randomly divided into 2 groups ( n = 30 each) : control group (group C) and intraoperative wake-up test group (group W) . The intraoperative wake-up test was not performed during operation in group C. Anesthesia was induced with target-controlled infusion of sufentanil with the target effect-site concentration set at 0.5 ng/ml and iv injection of propofol 1-2 nig/kg. As soon as the patients lost consciousness, tracheal intubation was facilitated with 0.15 mg/kg cisatracurium besylate. The patients were mechanically ventilated. Anesthesia was maintained with target-controlled inhalation of sevoflurane (target end-tidal concentration 0. 8%-1. 5%), target-controlled infusion of sufentanil (target effect-site concentration 0.2-0.3 ng/ml) and iv infusion of cisatracurium besylate 0.1 mg- kg-1·h-1 . In group W, the patients underwent the intraoperative wake-up test. Postoperative analgesia was provided with sufentanil. The occurrence of intraoperative awareness and postoperative delirium was recorded. Results No significant difference was found in the incidences of intraoperative awareness and postoperative delirium between the two groups. Conclusion The intraoperative wake-up test is not the risk factor for postoperative delirium in patients undergoing scoliosis surgery under analgesia with sufentanil, and inhibition of perioperative pain and intraoperative awareness by analgesia with sufentanil may be involved in the mechanism.
