Extravascular lung water index versus oxygenation index in estimation of severity of acute lung injury
10.3760/cma.j.issn.0254-1416.2011.03.014
- VernacularTitle:血管外肺水指数与氧合指数评估急性肺损伤程度准确性的比较
- Author:
Shan FENG
;
Qingsheng HUANG
;
Lixia ZHANG
;
Mingxing FANG
;
Jianying GUO
;
Zhiyong WANG
- Publication Type:Journal Article
- Keywords:
Extravascular lung water;
Blood gas analysis;
Respiratory distress syndrome,adult
- From:
Chinese Journal of Anesthesiology
2011;31(3):318-320
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare extravascular lung water index (EVLWI) and oxygenation index (PaO2/FiO2) in estimation of acute lung injury(ALI) .Methods Sixteen patients with post traumatic ALI (within 48 h) of both sexes, aged 18-80 yr, were studied. The patients were mechanically ventilated. Right internal jugular vein and femoral artery were catheterized and connected to PiCCO monitor (IntelliVue MP50, Philips, Netherlands).EVLWI was monitored with the PiCCO system. PaO2 was determined every 24 h. ALI was diagnosed based on the following criteria:(1)PaO2/FiO2≤300 mm Hg; (2)X-ray chest film-patchy shadows in the bilateral lungs and (3) CVP≤12 mm Hg.Lung injury score(LIS) was recorded. The patients were divided into PaO2/FiO2≤ 300 group and ≤200 group and EVLWI ≥ 10 group and ＜ 10 group. Results There was no significant difference in LIS between PaO2/FiO2 ≤300 group and PaO2/FiO2 ≤200 group at 24 and 48 h of PiCCO monitoring. At 72 h of PiCCO monitoring LIS was significantly increased in PaO2/FiO2 ≤200 group as compared with PaO2/FiO2 ≤300 group, LIS was significantly higher in EVLWI≥ 10 group than in EVLWI ＜ 10 group at 24, 48 and 72 h of PiCCO monitoring. Conclusion EVLWI is more accurate than PaO2 /FiO2 in estimation of severity of ALI.
