Clinical significance of CRP、neutrophil granulocyte ratio in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease
10.3760/cma.j.issn.1008-6706.2011.13.010
- VernacularTitle:C反应蛋白、中性粒细胞比例在慢性阻塞性肺疾病急性加重期的意义
- Author:
Dongming HUANG
;
Xiaofeng ZHOU
- Publication Type:Journal Article
- Keywords:
Pulmonary disease,chronic obstructive;
C-reactive protein;
Leukocyte count
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(13):1747-1749
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance of C-reactive protein(CRP),neutrophil granulocyte ratio(N% ) in acute exacerbations of hospitalized patients with chronic obstructive pulmonary disease ( COPD ). Methods The serum CRP levels,the gross of N% were detected of the same 71 patients with acute exacerbations of COPD before treatment and after getting better. And the correlations among above-mentioned indexes,the days counter before getting better and the days counter during hospitalization were observed. Results (1) The levels of CRP and N% of patients after getting better were significantly lower than those before treatment(P ＜0. 01). (2) There was a significant correlation between N% and the days counter before getting better(r =0.240,P ＜0.05) and also a significant correlation between the days counter before getting better and the days counter during hospitalization (r = 0. 567, P ＜0.01). Conclusion The serum CRP level and N% were objective markers in estimating pulmonary infection in COPD patients with acute exacerbations. And N% was a reliable indicator of judging the days counter before getting better and better than CRP.
