Tumor stem cells and tumor angiogenesis
10.3760/cma.j.issn.1673-422X.2011.05.002
- VernacularTitle:肿瘤干细胞与肿瘤血管生成
- Author:
Xiaohui LI
;
Weidong ZHANG
- Publication Type:Journal Article
- Keywords:
Neoplastic stem cells;
Neovascularization,pathologic;
Vascular endothelial growth factors
- From:
Journal of International Oncology
2011;38(5):326-328
- CountryChina
- Language:Chinese
-
Abstract:
The process of tumor angiogenesis is a complicated chain reaction which happens under the action of a series of positive feedback and negative feedback factors . Cancer stem cells are small part cell groups of self-renewal and multilineage differentiation potential in tumors. Many studies indicate that tumor stem cells participate in the process of tumor angiogenesis, and vascular endothelial growth factor can regulate endothelial proliferation and angiogenesis, thereby promoting tumor growth and metastasis.
