Cholangiocarcinoma: risk factor and related pathomechanism
10.3760/cma.j.issn.1007-8118.2011.07.026
- VernacularTitle:胆管癌的危险因素及相关病理机制
- Author:
Haolu WANG
;
Chaofeng ZHANG
;
Jian WANG
- Publication Type:Journal Article
- Keywords:
Cholangiocarcinoma;
Risk factor;
Pathomechanism
- From:
Chinese Journal of Hepatobiliary Surgery
2011;17(7):594-596
- CountryChina
- Language:Chinese
-
Abstract:
Cholangiocarcinoma is rare. It is highly malignant and early diagnosis is difficult. Various risk facts have been linked to the carcinogenesis and development of cholangiocarcinoma. Chronic inflammation and cholestasis are the two common pathways in the malignant transformation of cholangial cells. We reviewed the molecular biological researches of cholangiocarcinoma from two aspects: its risk factors and related pathomechanism.