Is contrast enhanced ultrasonography helpful to assessment of myometrial invasion in endometrial carcinoma in stage Ⅰ
10.3760/cma.j.issn.1004-4477.2011.07.019
- VernacularTitle:超声造影对Ⅰ期子宫内膜癌分型的价值探讨
- Author:
Xiaoqing PEI
;
Yanjun XIE
;
Yuhong LI
;
Yonghong XIONG
;
Wei ZHENG
;
Anhua LI
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Endometrial neoplasms;
Neoplasm staging
- From:
Chinese Journal of Ultrasonography
2011;20(7):598-601
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the accuracy of contrast enhanced ultrasonography (CEUS) in determining the depth of myometrial invasion in endometrial carcinoma in stage Ⅰ.Methods Seventy-six patients previously diagnosed of endometrial carcinoma by curettage of uterine underwent transabdominal sonography (TAS) and CEUS to assess myometrial invasion,among which 48 patients proved to endometrial carcinoma in stage Ⅰ after total abdominal hysterectomy and bilateral salpingo-oophorectomy were studied.The findings of TAS and CEUS to determine endometrial carcinoma IA (no myometrial involvement or invasion of the inner half of the myometrium) and IB( invasion of the outer half of the myometrium) were compared with pathology after abdominal hysterectomy.Results Twenty one tumours (43.75%,21/48) were enhanced earlier than or simultaneously as myometrium and cervix,among which 12 cases were IA stages,while 9 cases were IB stages (P<0.05);and 27 tumors (56.25%,27/48)were enhanced late than myometrium and cervix.There was no statistical difference between TAS and CEUS in detecting endometrial carcinoma in IA and IB(P>0.05).The sensitivity,specificity,positive predictive value,negative predictive value and accuracy of TAS and CEUS in diagnosing endometrial carcinoma in IB were 61.25% vs 69.23%,77.14% vs 85.71%,50.00% vs 64.28%,72.92% vs 88.23%,72.92% vs 81.25% respectively.Conclusions CEUS is not superior to TAS in detecting deep invasion of endometrial carcinoma in stage Ⅰ.
