Assisting stress ultrasound elastography with quantitative histography of distribution of stiffness for the age determination of venous thrombi: evaluation in an ex-vivo model of venous thrombosis
10.3760/cma.j.issn.1004-4477.2011.07.013
- VernacularTitle:助力式超声弹性成像测定血栓组织高硬度区域面积在体外静脉模型血栓分期中的应用价值
- Author:
Lei WANG
;
Ming CHEN
;
Weihua WU
;
Yue CHEN
;
Lianghua XIA
;
Chao WANG
;
Yong ZHU
;
Jie ZHANG
;
Lei ZHU
;
Qizhi LIU
;
Ling YANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Venous thrombosis;
Elastography
- From:
Chinese Journal of Ultrasonography
2011;20(7):583-586
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of assisting stress ultrasound elastographic quantitative parameter in determination of the thrombus age in an ex-vivo model of venous thrombi.MethodsAfter 1,3,6 and 9 days,9 saphenous vein samples with venous thrombosis were scanned by both tissue touch elasticity image and acoustic radiation force impulse (ARFI) respectively.For each group of thrombus age,a mean sheer strain was calculated in all thrombosis samples of the respective age.Furthermore,correlation of two sample data was analysed.Results The stiffness of thrombus age group of 1,3,6 and 9 days by tissue touch elasticity image were (49.23±14.91)%,(68.75±10.03)%,(80.82±10.29)% and (91.98±4.10)% respectively with significant differences among the parameters (P<0.05).Quantitative data of thrombus age groups correlated positively by two kinds of these elasticity image significantly (r=0.702,P=0.000).Conclusions The assisting stress ultrasound elastographic method with HM% in this experiment setting of venous thrombosis is proved to be helpful in determination of the age of venous thrombi.The present results obtained in our experiment might provide a potential application in evaluation of deep vein thrombosis by the elastographic technology clinically.
