Correlational study of ultrasonic elastography quantitative analysis with pathological stages of hepatic fibrosis
10.3760/cma.j.issn.1004-4477.2011.04.013
- VernacularTitle:弹性成像定量分析与肝纤维化分期的相关性研究
- Author:
Jie ZENG
;
Rongqin ZHENG
;
Zhongzhen SU
;
Jie REN
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Liver cirrhosis;
Elastography
- From:
Chinese Journal of Ultrasonography
2011;20(4):311-313
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility of evaluation of hepatic fibrosis using the tissue dispersion quantitative analysis software based on ultrasonic elastography. Methods Forty-six chronic liver disease patients were examined by tissue dispersion quantitative analysis software. There were 11 characteristic quantities of elastography imaging obtained by the tissue dispersion quantitative analysis software,including average relative strain value,standard deviation of relative strain value,area ratio of low-strain region ( AREA%) , complexity, kurtosis, skewness, contrast, entropy, inverse different moment,angular second moment,correlation. The 11 characteristic quantities were compared with pathological stages of hepatic fibrosis. Results The characteristic quantities had statistically significant differences except kurtosis and correlation in the analysis of variance and correlational study with pathological stages ( P < 0.05). The AREA% had the highest related coefficient ( r = 0.725). The ROC curve was made by AREA% ,the areas under the ROC curve were 0. 865 ,0. 880 and 0. 886. Conclusions The tissue dispersion quantitative analysis software is helpful in the evaluation of stages of hepatic fibrosis. The AREA% has the highest relationship with pathological stages of hepatic fibrosis and good diagnostic value.
