The diagnostic value of positive 99Tcm-MIBI tumor imaging for thyroid cancer
10.3760/cma.j.issn.1008-6315.2011.08.021
- VernacularTitle:99Tcm-MIBI肿瘤阳性显像在甲状腺癌诊断中的价值
- Author:
Peng YU
;
Fengling GONG
;
Wenqing LI
;
Yongping LIANG
;
Ruixing SHANG
;
Linmei LI
;
Qiang MENG
- Publication Type:Journal Article
- Keywords:
Thyroid cancer;
Radionuclide;
99Tcm
- From:
Clinical Medicine of China
2011;27(8):841-843
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of positive 99Tcm-MIBI tumor imaging for thyroid cancer diagnosis. Methods Fifty four suspected thyroid cancer patients underwent 99Tcm-O4 and 99Tcm-MIBI combined imaging procedure. The imaging data were confirmed by pathological findings. Results All the 54 cases had single throid nodules, and 25 of which were pathologically malignant. Fifty two cases of nodules were detected by the 99Tcm O4 thyroid static imaging, including 2 hot nodules,4 warm nodules, 10 cool nodules and 36 cold nodules;2 cases were negative by the imaging. Of the 25 malignant thyroid nodules, 16 nodules were visible by 99Tcm-MIBI uptake and were cold nodules;29 exhibited benign thyroid nodules,of which 15 could be seen by 99Tcm-MIBI uptake,including 1 warm nodules,2 cool nodules and 12 cold nodules. The sensitivity, specificity of the combined imaging of 99Tcm O4 and 99Tcm-MIBI were 64. 00% ( 16/25 ) and 48. 28% (14/29). No significant difference was found for the positivity between benign nodules and malignancy nodules by 99Tcm-MIBI tumor imaging ( χ2 = 0. 83, P ＞ 0. 05 ). Conclusion 99Tcm-MIBI tumor imaging is not specific for the diagnosis of thyroid malignancy.
