Features of MRI in the patients with multiple system atrophy
10.3760/cma.j.issn.1008-6315.2011.07.013
- VernacularTitle:多系统萎缩患者头部磁共振的神经影像学特点
- Author:
Yingshan PIAO
;
Tao FENG
- Publication Type:Journal Article
- Keywords:
Multiple system atrophy;
Parkinson disease;
MRI
- From:
Clinical Medicine of China
2011;27(7):705-708
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the features of magnetic resonance imaging(MRI)in the brain of patients with multiple system atrophy(MSA)and compare with that in Parkinson Disease(PD).Methods Thirteen patients with MSA-C,12 patients with MSA-P,and 30 patients with Pakinson disease(PD)were retrospectively studied in terms of MRI data.Results The area of the pons in the patients with MSA-C(386.4±74.2)mm2 was significantly smaller than in those with PD(528.5±40.8)mm2,as well as the average of the pons transverse diameter([17.9±1.8]mm in the patients with MSA-C and[20.2±1.4 lnun in PD patients)(t=6.5 and 4.7,Ps<0.01).The area of the pons in MSA-P patients(474.1±88.0)mm2 and the average of the pons tranverse diameter(19.3±2.4)mm were similar to those of PD patients(Ps>0.05).The average width of middle cerebellar pedncles(MCP)in MSA-C(6.1±1.6)mm and MSA-P(6.5±1.2)mm were smaller than those in PD patients(9.1±1.0)mm(t=6.2 and 7.1,Ps<0.01),whereas there was no significant difference between MSA-C and MSA-P group(P>0.05).In the MRI findings,cerebellar atrophy was the highest sensitive,and cruciform hyperintensity and hyperintensity of MCP followed.The MBI profiles were more specific for hyperintensity of cruciform and MCP than for cerebellar atrophy in MSA-C population.For MSA-P population,MRI was relatively sensitive for hyperintensity of rim of the putamen and putamen,but less specific.Conclusion The assessment of MRI may be useful to diagnose and distinguish MSA from PD.
