The clinical pathological analysis of Epstein-Barr virus active infection during the middle-late pregnancy

VernacularTitle:妊娠中晚期急性EB病毒感染的临床研究
Author: Min ZHONG ; Ruojin YAO ; Yan TIAN
Publication Type:Journal Article
Keywords: Herpesvirus 4,human; Herpesviridae infections; Hydrops fetalis/ET; Pregnancy trimester,third; Pregnancy outcome
From: Journal of Chinese Physician 2011;13(5):615-617
CountryChina
Language:Chinese
Abstract: Objective To explore the relationship of acute infections of Epstein-Barr virus and hydrops fetalis and explore the harm to fetuses and the affection on pregnancy outcomes caused by acute EBV infection during pregnancy. Methods 40 cases hydrops fetalis were diagnosed by ultrasonography. The difference between the EBEA-IgM positive and negative patients blood were studied. 101 cases over the same period of pregnant women with normal fetuses were enrolled as a control group. Results The positive rate of EBEA-IgM in pregnant women (95%) was significantly higher than that of control group(48.5%,P＜0.01). And the differences of the ratio of still birth and live birth and abnormal fetuses induction of labor between the groups were statistically significant（P＜0.01）. Premature birth among the live birth (40%) was obviously higher than that of control group (10.9%,P＜0.05). Conclusions Active infection of EBV in pregnancy was relevant to the hydrops fetalis and there need to pay attention to the detection of EBV during pregnancy.