Hyperlactatemia and metabolic acidosis in critically ill patient
10.3760/cma.j.issn.1674-635X.2011.03.011
- VernacularTitle:重症患者的高乳酸血症与代谢性酸中毒
- Author:
Wei DU
;
Dawei LIU
- Publication Type:Journal Article
- Keywords:
Lactate;
Lactic acidosis;
Acid-base balance
- From:
Chinese Journal of Clinical Nutrition
2011;19(3):183-187
- CountryChina
- Language:Chinese
-
Abstract:
The relationship between hyperlactatemia and metabolic acidosis, which may involve shock resuscitation,homoiostasis, and nutritional support, remains a hot topic. On one hand, increased production of lac-tate due to anaerobic glycolysis during tissue hypoperfusion can aggravate metabolic acidosis; on the other hand,the utilization of lactate at organ and cell levels may lower blood lactate level, and thus alleviate metabolic acidosis.The ultimate blood lactate level depends on the balance of these two action mechanisms.
