Observation on the effect of edaravone in treatment of patients with acute cerebral infarction

VernacularTitle:依达拉奉治疗急性脑梗死96例疗效观察
Author: Jiangnan TAN
Publication Type:Journal Article
Keywords: Edaravone; Cerebral infarction; Hemorheology
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(14):1886-1887
CountryChina
Language:Chinese
Abstract: Objective To observe the effect of edaravone on haemorheology in the patients with cerebral infarction. Methods 96 patients with cerebral infarction were collected and randomly divided into observation group and control group. 48 patients were divided into each group. Conventional thrombolysis therapy was used in control group,and salvia miltiorrhiza intervenous drop infusion after thrombolysis. Edaravone intervenous drop infusion after thrombolysis was used in observation group. The curative effect,neurologic impairment score,and the haemorheology index(the whole reduced viscosity,hematocrit, ESR and fibrinogen) were detected in all patients. Results All the patients got a good curative effect, the improved neurologic impairment score and the haemorheology index after different treatment. The curative effect,the neurologic impairment score and the haemorheology index were better in observation group after treatment than that in control group (all P＜0. 05). Conclusion Edaravone could play'a better therapeutical effect in patients with cerebral infarction by cleaning the free radical and improving the state of haemorheology.