Immunological study of lymphangiogenesis in pterygium pathogenesis
10.3760/cma.j.issn.1673-4904.2011.21.006
- VernacularTitle:新生淋巴管与翼状胬肉发病机制的免疫学研究
- Author:
Xiaowei ZHANG
;
Yuanhong ZENG
;
Haotian LIN
- Publication Type:Journal Article
- Keywords:
Pterygium;
Lymphangiogenesis;
Immunological reaction
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(21):14-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective To confirm the effect of lymphangiogenesis in immunological reaction on pterygium formation and development.Methods The clinical removal of pterygium material in quiescent phase,advanced phase and recurrent phase was selected.each phase with 12 cases,while 10 cases of normal bulbar conjunctiva were taken as control.5'-nueleotide enzyme-alkallne phosphat&se-double enzyme histochemistry was performed to compare the number of lymphangiogenesis in different tissues.Results Lymphangiogenesis in normal bulbar conjunctiva and quiescent phase pterygium tissues expressed little,but gray-stained lymphangiogenesis widely distributed in pterygium tissue of advanced phase and recurrent phase,and there were statistically significant differences compare those with the normal bulbar conjunctiva and quiescent phase pterygium(P=0.03 and 0.01).Conclusion Lymphangiogenesis may be involved in immunity process of pterygium pathogenesis.
