Clinical observation of ximingtingpian in treatment of osteoporosis result in hypofunction of ovary
10.3760/cma.j.issn.1673-4904.2011.21.002
- VernacularTitle:希明婷片对卵巢功能低下所致骨质疏松症的疗效观察
- Author:
Chunyan ZHANG
;
Zhongli YANG
- Publication Type:Journal Article
- Keywords:
Perimenopause;
Ovarian failure,premature;
Osteoporosis;
Ximingting
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(21):4-6
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effects of ximingting plan in treatment of osteoporesis result in hypofunction of ovary.Methods Sixty women with osteoporesis result in hypofunefion of ovary were divided into two groups by random digits table with 30 cases each.The investigated group received ximingting pian,the controlled group received hormone replacement therapy(HRT).The changes of bone density,bone gla protein(BGP),estradiol,follicle-stimulating hormone(FSH),the thickness of endometrium,blood routine,urine routine,liver function and kidney function before and after 6 months treatment were measured.Results Bone density and BGP after treatment wag higher than that before treatment in two (6.78±3.97)g/L;in controlled group:(0.617±0.065)g/cm2 vs.(0.552±0.073)g/cm2 and(8.92 4±4.43)g/L vs.(6.83±4.29)g/L](P<0.05).The levels of estradiol and FSH had no marked changes in investigated group(P>0.05);but not this in controlled group(P<0.01).The total effective rate of curative effect and presenting symptom was 93.3%(28/30),93.3%(28/30)in investigated group and 90.0%(27/30),86.7%(26/30)in controlled group,there was no significant difference between two groups(P>0.05).There was no significant difference in blood routine,urine routine,liver function and kidney function before and after treatment in two groups(P>0.05).Conclusion Ximingting pian is efficacious and safe in the treatment of osteoporosis result in hypofunction of ovary.
