Efficacy of tacalcitol ointment combined with desonide cream in the treatment of plaque vulgaris psoriasis
10.3760/cma.j.issn.1673-4904.2011.18.006
- VernacularTitle:他卡西醇软膏联合地奈德乳膏治疗寻常型斑块状银屑病的疗效观察
- Author:
Yadong MENG
- Publication Type:Journal Article
- Keywords:
Tacalcitol;
Desonide;
Psoriasis
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(18):14-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of tacalcitol ointment combined with desonide cream in the treatment of plaque vulgaris psoriasis. Methods Sixty-six patients with plaque vulgaris psoriasis were assigned into combination treatment group and desonide sole treatment group by random digits table with 33 cases each. In combination treatment group, desonide cream was applied 1 time per day in the morning and tacalcitol ointment was applied 1 time per day at night. In desonide sole treatment group, desonide cream was applied twice one day. The therapy for two groups continued for 8 weeks. Results The total effective rate in combination treatment group was 78.79%( 26/33 ), and it was lower than that in desonide sole treatment group [84.85%(28/33)],but there was no significant difference between two groups (P>0.05). The recurrence rate was 25.00% (7/28) in desonide sole treatment group and 11.54% (3/26) in combination treatmentgroup,there was no statistical difference between two groups (P >0.05). There was no serious side effect during observation. Conclusions Tacalcitol ointment combined with desonide cream has no more effective for plaque vulgaris psoriasis than that of desonide cream alone. The combined use of these two drugs could reduce the dosage of steroid and side effect.
