Analysis on high risk factors for recurrent bladder cancer after radical operation on upper urinary tract transitional cell carcinoma
10.3760/cma.j.issn.1673-4904.2011.17.012
- VernacularTitle:上尿路移行上皮细胞癌根治术后复发膀胱肿瘤的高危因素分析
- Author:
Shuo LIU
;
Wenlong MIAO
;
Fengqi LI
;
Zhe WANG
;
Guang SUN
- Publication Type:Journal Article
- Keywords:
Ureteral neoplasms;
Recurrence;
Bladder neoplasms;
Upper urinary tract transitional cell arcinoma
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(17):29-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between tumor location and the risk of developing bladder cancer in pafients treated by nephroureterectomy(NU)for upper urinary tract transitional cell carcinoma(UUT-TCC).Methods The clinical data of 168 UUT-TCC patients who underwent NU were reviewed.Univariate and multivariate analysis were carried out to determine the risk factors for intravesical recurrence after NU.Results The recurrence-free survival rate at 1,3 and 5 years after NU were 88%, 76%and 63%.All patients were followed up for a median period of 45(12-107)months During this period, a total of 49 patients developed bladder tamors after surgery,of which 28 cases were renal pelvic carcinoma, 2 cases were rniddle ureter carcinoma and 19 cases were distal ureter carcinoma.The recurrence-free survival of renal pelvic carcinoma and ureter carcinoma had no significant difference by Log-Rank test(P>0.05).On multivariate analysis,only locating in distal ureter carcinoma was the independent risk predictor for intravesical recurrence after NU (P<0.01).Conclusion Pafients with UUT-TCC at distal ureter carry a higher risk for intraeesieal recunerrce after NU than those with TCC at other location of upper urinary tract.
