The role of brain natriuretic peptide in cardiac surgery

VernacularTitle:脑钠肽在心脏外科手术中的作用
Author: Yili MA ; Xijing ZHUANG ; Guanran LI ; Xuezhi HE ; Yongcai LIANG
Publication Type:Journal Article
Keywords: Natriuretic peptide,brain; Cardiac surgical procedures
From: Chinese Journal of Postgraduates of Medicine 2011;34(17):24-26
CountryChina
Language:Chinese
Abstract: Objective To investigate the influence of brain natrluretic peptide(BNP) in the prognosis of cardiac surgery.Methods Selected 115 cases of pafients with the first cardiac surgery.Their BNP concentration was measured before operation. Observed the relationship between BNP and postoperative atrial fibrillation,mechanical ventilation time,hospital stay,and the mortality of 30 d.Results Whether the patients had hypertension,diabetes,myocardial infarction history,left main stem disease and hemoglobin level or not,showed no definite relationship with BNP (P>0.05).Preoperative lower left ventricular ejection fraction (LVEF)(P=0.002) and European system for cardiac operation risk evaluation [(5±3)scores](P=0.003) were associated with higher BNP level.Postoperative mechanical ventilation time was(15.0±5.4)h,hospital stay was (32±11) d,showed a clear relationship with BNP(P= 0.035,0.001),but postoperative mediastinal infection,atrial fibrillation and mortality of 30 d had no definite relationship with BNP(P>0.05).Conclusion BNP can be used to predict the risk after cardiac surgery.