Correlation study of arterial blood lactate levels and acute physiology and chronic health evaluation Ⅱ in critically ill patients
10.3760/cma.j.issn.1673-4904.2011.16.010
- VernacularTitle:危重病患者动脉血乳酸水平与急性生理学及慢性健康状况评分和预后相关性研究
- Author:
Yu LI
- Publication Type:Journal Article
- Keywords:
Critical illness;
Lactic acid;
APACHE
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(16):26-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between arterial blood lactate levels and acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ ) in critically ill patients.Methods Seventy-one patients with critical illness who treated in intensive care unit were included as research subjects and divided into death group with 16 cases and survival group with 55 cases according to the prognosis.The correlation between arterial blood lactate levels and APACHE Ⅱ was analyzed.Results With the increase of APACHE Ⅱ ,arterial blood lactate levels and mortality all increased significantly.The blood lactate levels reached (8.20±3.52) mmol/L and mortality was 64.7%(11/17) when APACHE Ⅱ >30 scores,and there were significant differences between different segment of APACHE Ⅱ (P <0.05).Linear correlation analysis showed:arterial blood lactate levels were positively correlated to APACHE Ⅱ significantly (r = 0.563,P <0.05).The APACHE Ⅱ and arterial blood lactate levels in the death group were (29.7 ± 6.9) scores and (7.6 ±4.1) mmol/L respectively,which were significantly higher than those in the survival group [(18.3 ± 7.0) scores and(3.0 ± 1.7) mmol/L].The differences between two groups were statistically significant (P＜0.05).Conclusion The arterial blood lactate levels of critically ill patients are positively related to APACHE Ⅱ ,and its level has an important clinical significance in judging the severity and the prognosis of the illness.
