Magnetic resonance findings of hepatocellular carcinoma after transcatheter arterial chemoembolization
10.3760/cma.j.issn.1673-9752.2011.03.026
- VernacularTitle:肝癌肝动脉栓塞化疗后磁共振成像检查特征
- Author:
Jia WANG
;
Yan ZHONG
;
Yan WANG
;
Huiyi YE
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Transcatheter arterial chemoembolization;
Magnetic resonance imaging
- From:
Chinese Journal of Digestive Surgery
2011;10(3):231-233
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocelular carcinoma ( HCC) is one of the most common causes of cancer death worldwide. Although surgical resection offers a better curative option than nonsurgical treatments, it is not an option for the majority of patients with poor hepatic function or at an advanced stage when diagnosed.Transcatheter arterial chemoembolization (TACE) is an alternative and effective nonsurgical treatment for HCC. Evaluation of the effect of TACE is important to develop a best therapeutic strategy. From January 2009 to December 2010, 28 patients with HCC received TACE at the PLA General Hospital, and the results of magnetic resonance imaging ( MRI) were analyzed. Fifty-one lesions were detected and the maximum diameter of the lesions was 14.7 cm. Twenty-eight lesions in 16 patients which showed variable signal intensity on T1- and T2 -weighted images and iso- or hypointensity on diffusion-weighted image ( DWI) had no enhancement. Five lesions of 10 tumors in four patients had focal enhancement in the first MRI after TACE that displayed hyperintensity on DWI. Eight patients had been found with tumor recurrence or metastasis when they received MRI for the second time. The recurrent, residual and intrahepatic metastatic tumors enhanced rapidly at dynamic early phase scanning and demonstrated hyperintensity on T2 -weighted images.
