Study on the extracting method of salviae miltiorrhizae madix et rhizoma in Huoluo-Xiaoling granules
10.3760/cma.j.issn.1673-4246.2011.07.009
- VernacularTitle:活络效灵颗粒中丹参的提取工艺研究
- Author:
Chao WANG
;
Yuanyan LIU
;
Qing LI
;
Lei XIA
;
Zhiqian SONG
;
Chun WANG
;
Yuna CAO
;
Zheng WEI
;
Linyan ZENG
;
Zhenli LIU
- Publication Type:Journal Article
- Keywords:
Huoluo-Xiaoling granules;
Salviae Miltiorrhizae Madix et Rhizoma;
Extraction method;
Salvianolic acid B;
Tanshinone ⅡA
- From:
International Journal of Traditional Chinese Medicine
2011;33(7):605-608
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the extraction method of salviae miltiorrhizae madix et rhizoma in Huoluo-Xiaoling granules. Methods According to the contents of Salvianolic acid B and Tanshinone Ⅱ A, the extraction method was established by comparing different solvents (water and 70% ethanol)and extracting modes (compound extraction and single herb extraction). Then orthogonal design was used to determine the optimum extraction method. Results Considering the contents of salvianolic acid B and tanshinone Ⅱ A, 70% ethanol extract was better than water extract and compound extraction was better than single herb extraction.The optimum extraction condition was 70% ethanol in eight times of the herbs weight, extracted for 1h by 3times. Conclusion The extraction method was simple and stable.