Effect of Xuebi-jing injection on serum high-sensitivity C-reactive protein in acute exacerbation of chronic obstructive pulmonary disease (AECOPD)
10.3760/cma.j.issn.1673-4246.2011.06.004
- VernacularTitle:血必净注射液对慢性阻塞性肺疾病急性发作期血清超敏C反应蛋白的影响
- Author:
Dayong CHEN
;
Zhuoji LI
;
Bilin CAI
- Publication Type:Journal Article
- Keywords:
Xuebi-jing injectiong;
Acute exacerbation of chronic obstructive pulmonary disease;
High-sensitivity C-reactive protein
- From:
International Journal of Traditional Chinese Medicine
2011;33(6):491-493
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Xuebi-jing injection on the change of the serum high-sensitivity C-reactive protein (hs-CRP) in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Methods 86 patients with AECOPD were enrolled in this study, who was randomly divided into a control group (43 cases)and a treatment group (43 cases). Both treatment group and control group were given conventional therapy. On this basis, Xuebi-jing injection was added to the treatment group. Hs-CRP, blood gas analysis, blood cell count and severity of illness score (acute physiological and chronic health evaluation Ⅱ, APACHE Ⅱ) were monitored before and 5 days after treatment. Results There was no obvious difference of hs-CRP levels between two groups before treatment. Hs-CRP was decreased in both groups after the treatment, while the treatment group showed an obvious decrease compared with the control group (t＝5.3302,P＜0.01). Blood gas analysis, blood cecount, APACHE Ⅱ scores were improved after the treatment in both groups, while the improvement in treatment group showed obvious difference than the control group (t＝13.5089、26.3077 、13.4053,P＜0.01). Conclusion The conventional therapy plus Xuebi-jing injectiong for AECOPD can improve serum hs-CRP levels and improve the efficacy of AECOPD .
