Clinical research on the treatment of cough variant asthma with modified Zhisou powder and symbicort turbuhaler simultaneously
10.3760/cma.j.issn.1673-4246.2011.06.003
- VernacularTitle:止嗽散加味颗粒剂联合信必可治疗咳嗽变异性哮喘的临床研究
- Author:
Qun ZHANG
;
Jizhong CHEN
;
Xuehui SUN
;
Hui GUO
;
Lezhi HOU
- Publication Type:Journal Article
- Keywords:
Cough variant asthma;
Modified Zhisou powder;
Symbicort turbuhaler
- From:
International Journal of Traditional Chinese Medicine
2011;33(6):487-490
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect of modified Zhisou powder and Symbicort Turbuhaler simultaneously on patients with Cough Variant Asthma. Methods 120 patients with Cough Variant Asthma were randomly recurited into two groups. 60 patients in the treatment group were treated with modified Zhisou powder and Symbicort Turbuhaler; 60 patients in the control group were treated with Symbicort Turbuhaler. 4 weeks was a therapeutic course in both group. Results The markedly controlled rate (MCR) (clinical control+excenence)of the treatment group was 83.3%, obviously surpassed the control group (70.0%) (P＜0.05); There was obvious improvement of cough, expectoration, breath lessness and throaty pruritus after the therapy in both groups, but it was much better in the treatment group than the control group(P＜0.05). The pulmonary function was significantly improved after treatment in both groups(FEV1, FEV1% and PEF, P＜0.05). The improvement showed significant difference between the two groups(P＜0.05). There was obvious decrease of EOS, IL-5 and ECP in both groups. The decrease of ECP and IL-5 in the treatment group was greater than the control group(P＜0.01). Conclusion The therapy of modified Zhisou powder and Symbicort Turbuhaler has advantage over pure western therapy.
