Important trials of targeted therapy in patients with advanced gastric carcinoma
10.3760/cma.j.issn.1673-422X.2011.07.020
- VernacularTitle:胃癌分子靶向治疗的临床研究进展
- Author:
Baihong ZHANG
;
Xianghui WANG
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Drug therapy;
Clinical trial
- From:
Journal of International Oncology
2011;38(7):543-544
- CountryChina
- Language:Chinese
-
Abstract:
The conventional treatment options for advanced gastric carcinoma patients remain unsatisfactory in terms of response rate and overall survival benefit. Targeted therapy plus systemic chemotherapy now becomes a new promising therapeutic option. In this review we profiled important trials of international multicenter phase Ⅲ clinical studies in patients with advanced gastric carcinoma, including ToCA trial, EXPAND trial, LOGIC trial, AVAGAST trial, REAL3 trial, and granite-1 trial. These trials warrant the role of molecular targeted therapy in patients with advanced gastric carcinoma.
