Aberrant methylation in lung cancer
10.3760/cma.j.issn.1673-422X.2011.07.017
- VernacularTitle:异常甲基化与肺癌
- Author:
Lin HU
;
Dan SU
;
Yiping ZHANG
- Publication Type:Journal Article
- Keywords:
Methylation;
Lung neoplasms;
Tumor markers,biological
- From:
Journal of International Oncology
2011;38(7):533-536
- CountryChina
- Language:Chinese
-
Abstract:
Aberrant promoter methylation in special genes such as tumor suppressor genes is early eventin carcinogenesis of lung cancer. Aberrant methylation, resulting in corresponding mRNA silence or overexpression , closely relates to carcinogenesis, development, treatment response and prognosis of lung cancer and it may become a potential biomarker. Methylation of special genes may provide evidences for individual treatment of lung cancers.
