Identification and isolation of cancer stem cells
10.3760/cma.j.issn.1673-422X.2011.06.004
- VernacularTitle:肿瘤干细胞的鉴定与分离
- Author:
Zhiguang LIN
;
Bobin CHEN
- Publication Type:Journal Article
- Keywords:
Neoplastic stem cells;
Immunophenotyping
- From:
Journal of International Oncology
2011;38(6):411-414
- CountryChina
- Language:Chinese
-
Abstract:
Cancer stem cells are considered to be the origin of tumor relapse.Isolating and identifying them by special immune-phenotypes is the most commonly used method.The technique of isolating SP cells is very mature.More attentions are being paid to the isolation of cancer stem cells using differential expression activities of Wnt pathway on surface of tumor cells.Establishing stem cells niches to capture cancer tumor cells remains to be further evaluated.