Establishment of gastric cancer model in nude mice
10.3760/cma.j.issn.1673-4203.2011.07.013
- VernacularTitle:建立胃癌裸鼠模型的研究进展
- Author:
Yunpeng ZHANG
;
Peng SUN
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Mice,nude;
Animal model
- From:
International Journal of Surgery
2011;38(7):472-474
- CountryChina
- Language:Chinese
-
Abstract:
The establishment of animal model is fundamental to the experimental studies. It involves the selection of animals and cell lines, the determination of the number of cells and the option of the ways of transplant. Only when each production step is operated by following the occurrence and the development mechanism of the gastric cancer, can we simulate the process of growth of the gastric cancer in human body.Due to their congenital immune deficiency, the nude mice serve a better choice for the establishment of gastric cancer animal model. Beyond that, the cell lines selection and transplant way option also play important roles.
