Effects of cannabinoid receptors and their ligands on gastrointestinal motility and secretion
10.3760/cma.j.issn.1673-4203.2011.07.012
- VernacularTitle:大麻素受体和配体对胃肠运动及分泌的影响
- Author:
Minghua CAO
;
Yongyu LI
- Publication Type:Journal Article
- Keywords:
Cannabinoid receptor;
Endocannabinoid system;
Gastrointestinal motility;
Gastrointestinal secretion
- From:
International Journal of Surgery
2011;38(7):468-471
- CountryChina
- Language:Chinese
-
Abstract:
Endocannabinoid system has several kinds of receptors, all of which have correspondence ligands and pathways of synthesis and degradation, and they belong to G-protein coupled receptors family. Recently studies show that stimulation of cannabinoid receptors has inhibitory effects on gastrointestinal motility and secretion. In this article, we introduce the compositions of the cannabinoid family members, includingtheir receptors, ligands, and antagonists, and their effects on the gastrointestinal motility and secretion. Useful information can be provided for the further study on the effects of endocannabinoid system on gastrointestinal motility and secretion, providing theoretic evidences for clinical use of cannabinoid.
