Diagnosis and treatment for synchronous occurrence of gastrointestinal stromal tumor and digestive tract cancer: a report of 6 Cases
10.3760/cma.j.issn.1673-4203.2011.07.008
- VernacularTitle:胃肠间质瘤合并消化道癌六例诊治体会
- Author:
Peng ZHANG
;
Kaixiong TAO
;
Guobin WANG
- Publication Type:Journal Article
- Keywords:
Gastrointestinal stromal tumors;
Digestive tract neoplasms
- From:
International Journal of Surgery
2011;38(7):455-457
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical characteristics, diagnosis, treatment and prognosis of synchronous occurrence of gastrointestinal stromal tumor( CIST) and digestive tract cancer in 6 cases. Methods The clinical and pathologic data of 6 patients of synchronous occurrence of gastrointestinal stromal tumor and digestive tract cancer from January 2005 to September 2010 in Wuhan Union Hospital were analyzed retrospectively. Results In 4 cases both tumors were located in the same organ, in the other 2 cases tumors were located in the adjacent sites of digestive tract. Only 1 case was found both tumors by preoperative examination , and the others were found digestive tract cancer. Gastrointestinal stromal tumors were all in the very low risk group, the diameter of CISTs was less than 1 cm and the mitotic score was less than 2/50 HPF in all the cases. Digestive tract cancer showed no specical demonstrations both macroscopically and microscopically. Conclusions Clinical features of synchronous occurrence of CIST and digestive tract cancer are atypical. We should pay much attention to this entity in clinical practice. In this series, most CIST are in early stage and of low risk of malignance. The prognosis of patients with synchronous occurrence of GIST and digestive tract cancer mainly depends on digestive tract cancer.
