Analysis between the related factors,intima-media thickness of the lower peripheral arteries and maximal shear rate in diabetic patients

VernacularTitle:糖尿病下肢动脉内中膜厚度与血流最大剪切率及相关危险因素研究
Author: Pan CHENG ; Rongxiu WU
Publication Type:Journal Article
Keywords: Color Doppler ultrasound; Diabetes Mellitus; The Lower Peripheral Arteries; Maximal Shear Rate; Risk factors
From: International Journal of Biomedical Engineering 2011;34(2):118-121
CountryChina
Language:Chinese
Abstract: Objective To investigate the correlation of intima-media thickness (IMT) of the lower peripheral arteries and maximal shear rate (SR) in diabetic (DM) patients and to analyze the related risk factors.Methods A total of 84 diabetic patients and 46 controls were recruited in the study.Color Doppler ultrasonography technique was applied to observe the IMT,diameter(D) and hemodynamics of the lower peripheral arteries and the comparison with biochemical parameters was carried out in order to reveal their correlation to the pathological changes of vascular in DM patients.ResultsIn DM group,the SR was lower than that in control group (P＜0.05).The risk factors related to the lower peripheral arteries of DM patients also were significant difference to that of control group (P＜0.05).Conclusion The decrease of SR in diabetes patients can cause the thicker IMT,which is one of the important factors leading to atherosclerosis and is correlated to various risk factors for metabolic syndrome.