The roles of Musashil and Notch signaling pathways in neurogenesis after cerebral ischemia
10.3760/cma.j.issn.1673-4165.2011.05.010
- VernacularTitle:Musashil和Notch信号通路在脑缺血后神经发生中的作用
- Author:
Xuejuan LIU
;
Jinsheng YANG
- Publication Type:Journal Article
- Keywords:
Nerve tissue proteins;
RNA-binding proteins;
MSI1 protein,human;
Receptors,Notch;
Brain ischemia;
Nerve regeneration
- From:
International Journal of Cerebrovascular Diseases
2011;19(5):397-400
- CountryChina
- Language:Chinese
-
Abstract:
Musashil is an evolutionarily conserved RNA binding protein. It plays an important role in the aspects of maintaining stem cell state, differentiation and tumorigenesis. Notch signal pathway plays an important role in the proliferation of neural stem cells after cerebral ischemia. This article briefly introduces the structure and molecular characteristics of Musashil and Notch, and reviews the interaction in the neurogenesis of Musashil and Notch signaling pathway after cerebral ischemic reperfusion.
