Lymph node metastasis pattern in patients with T2 and middle thoracic esophageal squamous cell carcinoma
10.3760/cma.j.issn.1001-4497.2011.05.011
- VernacularTitle:T2胸中段食管鳞癌淋巴结转移特点和规律
- Author:
Kunshou ZHU
;
Feng WANG
;
Derong ZHANG
- Publication Type:Journal Article
- Keywords:
Esophageal carcinoma Carcinoma;
squamous cell Lymphatic metastasis Logistic models
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2011;27(5):289-290
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pattern of lymph node metastasis in patients with 17 and middle thoracic esophageal squamous cell carcinoma( ESCC). Methods Retrospective review the clinical data of 246 cases with T2 and middle thoracic esophageal squamous cell carcinoma who were treated by three-field lymphadenectomy. Analyze the relationship between clinical pathological factors and lymph node metastasis. Results Lymph node metastases were found in 129 of the 246 patients (52.4% ).The average number of resected lymph nodes was 25 per patient (rangel5 -59). The rates of lymph node metastasis were 28.9% in the neck, 28.5% in thoracic mediastinum and 22.0% in abdominal cavity for patients with T2 and middle thoracic ESCC. No significant difference in lymph node metastasis' rate was observed among the neck, thoracic mediastinum and abdominal cavity. Logistic-regression showed the length of tumor, tumor cell differentiation and angiolymphatic invasion were factors influencing lymph node metastasis. Conclusion Lymph node metastasis in T2 and middle thoracic ESCC has the characteristics of upward, downward and skip spreading. Patients with T2 and middle thoracic ESCC should be treated with radical surgery with three-field lymphadenectomy.
