The analysis of prognostic factors in treating variceal hemorrhage of liver cirrhosis and portal hypertension with transjugular intrahepatic portosystemic shunt
10.3760/cma.j.issn.0254-1432.2011.05.003
- VernacularTitle:经颈静脉肝内门体静脉分流术治疗肝硬化静脉曲张出血预后因素分析
- Author:
Shanshan YUAN
;
Guohong HAN
;
Ming BAI
;
Zhanxin YIN
;
Chuangye HE
;
Jianhong WANG
;
Xingshun QI
;
Kaichun WU
;
Daiming FAN
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Hypertension,portal;
Esophageal and gastric varices;
Gastrintestinal hemorrhage;
Prognosis;
Portasystemic shunt,transjngular intrahepatic
- From:
Chinese Journal of Digestion
2011;31(5):299-302
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the prognostic factors in treating variceal hemorrhage patients of liver cirrhosis and portal hypertension with transjugular intrahepatic portosystemic shunt (TIPS).Methods From January 2003 to December 2008, the data of 162 variceal hemorrhage patients with liver cirrhosis and portal hypertension treated with TIPS was collected, which included basic information, biochemical examination results within 7 days before the operation, regular follow-up observation after the surgery and survival data. The survival prognostic indexes were assessed with Cox regression model. Results The successful rate of TIPS was 99% (161/162). The median follow up duration was 21 months. Child-Pugh score and blood platelet count (PLT) were closely correlated with survival (P = 0. 003 and 0. 024). The total cumulative survival rate in patients with Child-Pugh score below nine (75%, 102/136) was higher than over nine (50%, 13/26) (χ2 = 9. 12,P=0. 003).The total cumulative survival rate of patients with PLT count over 47 ×109/L (74%, 82/112) was higher than below 47 × 109/L(66 %, 33/50, χ2 =4. 528, P = 0. 033). The one year after operation cumulative survival rate of liver function Child-Pugh class A, B, and C was 92%, 85%, 55% respectively. Conclusion Child-Pugh score and platelet count are independent predictable factors for the survival of variceal hemorrhage patients with liver cirrhosis and portal hypertension treated by TIPS. The risk increase after operation when Child-Pugh score over 9 and/or PLT count less 47×109 /L.
