The pathogen surveillance of rubella virus in Beijing from 2007 to 2010
10.3760/cma.j.issn.0254-5101.2011.05.004
- VernacularTitle:北京市2007-2010年风疹病原学监测
- Author:
Tiegang ZHANG
;
Jie YANG
;
Meng CHEN
;
Cheng GONG
;
Ming LUO
;
Jiang WU
;
Yingchun HUANG
- Publication Type:Journal Article
- Keywords:
Rubella virus;
Real-time PCR;
Gene type
- From:
Chinese Journal of Microbiology and Immunology
2011;31(5):403-405
- CountryChina
- Language:Chinese
-
Abstract:
Objective To clarify the pathogen for rubella in Beijing from 2007 to 2010. Methods Beijing Center for Disease Preventipn and Control ( CDC ) collected the specimens (including blood, urine and throat swab specimens) frqm clinically diagnosed rubella cases for serological test and virus isolation. The nucleic acid of rubella virus in clinical specimens and isolations was detected by real-time PCR. Results Fifty-five out of 99 blood specimens were positive for anti- rubella IgM. Fifty-one out of 99 clinically diagnosed rubella cases were confirmed as rubella cases by virus isolation. Seventy-two were confirmed as rubella virus infections with real-time PCR method for detecting the nucleic acid of rubella virus in clinical specimens. Compared with the sequences of reference strains of rubella virus, all of detected rubella virus belonged the IE gene type. Conclusion This study indicates that IE gene type virus was the predominant endemic rubella virus in Beijing.
