Research progress on induction of pluripotent stem cell from adult stem cell

VernacularTitle:成体干细胞诱导多能干细胞的研究进展
Author: Suwen QI ; Yong DAI ; Zhiguang TU
Publication Type:Journal Article
Keywords: Induce pluripotent stem cell; Embryonic stem cell; Mechanism
From: International Journal of Biomedical Engineering 2011;34(3):188-192
CountryChina
Language:Chinese
Abstract: It is confirmed that the adult cells can be re-programmed to embryonic stem cells(ESCs) by presenting some certain factors in oocytes in the clone process of animals. In recent years, some transcription factors that can induce pluripotent stem cells(iPS) have been identified and which made it possible to obtain induced pluripotent stem cells similar to embryonic stem cells. iPS provides a unique platform to study the pluripotent mechanism and to establish some specific disease models. This major scientific discovery can not only avoid the use of ES which involves ethics debate, but also lead the stem cell research to a new field.