Respiratory syncytial virus infections in children with respiratory tract inflammation during winter and spring in Urumchi
10.3760/cma.j.issn.0254-5101.2011.04.006
- VernacularTitle:乌鲁木齐地区冬春季小儿呼吸道感染者中呼吸道合胞病毒感染的研究
- Author:
Min ZHI
;
Jie HE
;
Bin ZHANG
;
Jie DENG
;
Yuan QIAN
;
Peiru XU
;
He SUN
- Publication Type:Journal Article
- Keywords:
Respiratory syneytial virus;
Subtype;
Respiratory tract infection
- From:
Chinese Journal of Microbiology and Immunology
2011;31(4):316-319
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the infections of respiratory syneytial virus(RSV)in children with respiratory tract inflammation and define its molecular epidemic features in Urumchi.Methods SamDles were collected from November 2006 to April 2007 in the People's General Hospital of Xinjiang Uygur Autonomous Region,including 112 respiratory secretions and 280 nasopharyngeal swabs. RSV and its subgroups were detected by nested PCR.The five positive amplicons selected randomly from all positive samples were sequenced and compared with other RSV in GenBank by BLAST and DNAStar.Results of all 392specimens.68 RSV G gene segments were tested.Among them,RSV lineage A occupied 93.3%,while B occuDied 6.7%.The identities between them were 63.1%-99.4%.Phylogenetic analysis defined that they belonged to two different clusters.Conclusion RSV was one of the important viruses leading to children's respiratory tract infections in the People's General Hospital of Xinjiang Uygur Autonomous Region during winter and spring from 2006 to 2007.RSV subtype A was the prevalent genotype in the hospital dunng this epidemics.
