Correlation between renal function and arterial stiffness of Uighur population over 35 years in Xinjiang area
10.3760/cma.j.issn.1001-7097.2011.05.003
- VernacularTitle:新疆地区维吾尔族35岁以上人群肾功能与动脉僵硬度的相关性
- Author:
Shuo PAN
;
Xiaomei LI
;
Yitong MA
;
Yining YANG
;
Xiang XIE
;
Fen LIU
;
Ding HUANG
;
Ying HUANG
;
Qi TANG
;
Bangdang CHEN
;
Xiang MA
;
Lei DU
;
Xia GAO
;
Yinghong WANG
;
Zixiang YU
- Publication Type:Journal Article
- Keywords:
Kidney function tests;
Glomerular filtration rate;
Arteriosclerosis;
Pulse wave velocity
- From:
Chinese Journal of Nephrology
2011;27(5):322-326
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation between renal function and arterial stiffness of Uighur population over 35 years old in Xinjiang area. Methods From October 2007 to March 2010, four-stage stratified random sampling method was applied to collect a total of 4312 Uighur people over 35 years old in Urumqi, Karamay, Fukang, Turpan area, Hotan prefecture, Yili Kazak autonomous prefecture and Altai prefecture. The data of these 4312 general urban and rural Uygur residents were complete. Simplified MDRD formula was used to calculate the estimate glomerular filtration rate (eGFR). Arm-ankle pulse wave velocity (b-aPWV) of both sides was measured and the average value was used in correlation analysis with eCFR, and then the associated risk factors were adjusted. Results The eGFR was negatively correlated with b-aPWV (r=-0.174, P<0.01). Multiple linear regression showed that after adjusting some risk factors such as age, sex, body mass index, systolic blood pressure, diastolic blood pressure, waist circumference, hip circumference, uric acid, fasting blood glucose, total cholesterol, triglycerides, low density lipoprotein, eGFR was still negatively correlated with b-aPWV (P=0.012). Conclusions In Uygur population over 35 years old in Xinjiang, the glomerular filtration rate is negatively correlated with arterial stiffness.
