Survival analysis of prognostic associated factors in the maintenance hemodialysis patients

VernacularTitle:影响维持性血液透析患者预后相关因素的生存分析
Author: Xiaozhou HU ; Shaoting WANG ; Jin ZHANG ; Yongshen LU ; Yan ZHANG ; Hong YANG
Publication Type:Journal Article
Keywords: Hemodiafiltration; Survival analysis
From: Chinese Journal of General Practitioners 2011;10(5):348-350
CountryChina
Language:Chinese
Abstract: One hundred and twenty one patients on maintenance hemodialysis ( MHD) from Januaury 2004 to Januaury 2009 in our hospital were enrolled in the study. Demographic characteristics, clinical data and causes of disease were documented, the survival probability was estimated with Kaplan-Meier method and the prognostic factors were analyzed with Cox regression model. The median follow-up duration was 28. 9 months. The 1,3, 5-year survival rates were 93. 0% , 66. 5% and 45. 8% respectively. By Kaplan-Meirie analysis, cardiovascular disease (x2 =6. 582, P =0. 010) , age of starting dialysis (x2= 12.439, P= 0.002), urea clearance index Kt/V ( x2 =7.633, P=0.006) and albumin levels ( x2 = 4.512, P= 0.034) were closely related to prognosis. Cox regression analysis showed Kt/V, cardiovascular disease and age of starting dialysis were independent prognostic factors ( relative risk were 3. 204, 2. 994, 2. 543 respectively).