Investigation of the value of multi-slice CT perfusion imaging on brain hemodynamic in patients with cerebral infarction

VernacularTitle:脑梗死患者脑血流动力学的多层螺旋CT灌注成像研究
Author: Zhenhua LIU ; Yifeng DU ; Jingguang LV ; Lin LU ; Xiao MAN ; Jianping CHEN ; Zhenfang LIU
Publication Type:Journal Article
Keywords: Tomography; Cerebral infarction; Hemodynamics
From: Chinese Journal of Geriatrics 2011;30(6):452-454
CountryChina
Language:Chinese
Abstract: Objective To study the value of CT perfusion imaging(CTPI)on brain hemodynamic of the aged with cerebral infarction. Methods The 48 patients who were doubted with cerebral infarction underwent 16-slice CT plain scanning and CTPI within 24 hours of onset. The cerebral blood flow(CBF), mean transit time(MTT)and time to peak(TTP)of contrast-medium in region of interest(FOV)were used as brain hemodynamic parameters in comparation with contralateral regions. All cases were followed up with MRI after 3-10 days. Results Ischemia lesion was found on CT plain scanning in 40.9% of patients, while 93.2% of patients showed abnormal perfusion on CTPI. The sensibility of CTPI in identifying ischemia area was 93.2%, and the specificity was 100%. CBF in research area was significantly reduced, MTT and TTP were remarkably increased in contrast to counterparts(P＜0.01). Conclusions CT perfusion imaging can sensitively reveal the hemodynamic condition of cerebral ischemia, which could provide the important information for early diagnosis and treatment of the elderly with brain infarction.