The analysis of thoracic esophageal tumor mobility during normal respiration with four-dimensional computed tomography
10.3760/cma.j.issn.1004-4221.2011.03.011
- VernacularTitle:四维CT测量平静呼吸下原发胸段食管肿瘤运动的初步研究
- Author:
Fujun YANG
;
Jian ZHANG
;
Hongsheng LI
;
Dongqing WANG
;
Changsheng MA
;
Dongping SHANG
;
Tao ZHOU
;
Baosheng LI
- Publication Type:Journal Article
- Keywords:
Tomography,X-ray computed,four-dimensional;
Esophageal neoplasms;
Neoplasms motion
- From:
Chinese Journal of Radiation Oncology
2011;20(3):208-210
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the motion characteristics of primary thoracic esophageal carcinoma with four-dimensional computed tomography(4DCT).Methods Sixteen patients with primary thoracic esophageal carcinoma received respiratory gated 4DCT imaging,mapping the GTV1-GTV10 on every patient's each subsequent CT image of 10 images in the full-respiratory phase,and measuring the displacement of each centre of GTV.These displacements and directions were analyzed on different segments of esophagus.Results The mean total lung volume and GTV volume was 2993.5 cm3,35.00 cm3 and 3362.12 cm3,34.84 cm'respectively on end-expiration and end-inspiration phases(t=12.36,P=0.000and t=-0.61,P=0.546).The total mean peak to peak displacement of GTV were 0.65 mm,0.55 mm,and 2.03 nnn in x,y-and z-axis direction,respectively(F=41.14,P=0.000).The motion in x-axis,y-axis and z-axis were 0.50 mm,0.48mm,1.23 mm in the upper segment(F=5.45,P=0.017),0.68 mm,0.62 mm,1.97 mm in the middle segment(F=27.74,P=0.000),0.72 mm,0.38 mm,3.05 mm in the lower segment,respectively(F=15.61,P=0.000).Conclusions The displacement of tumor in z axis is more notable than x-,y-axis in thoracic esophageal carcinoma.The displacement of tumor x-,y-and z-axis is different in different segment of thoracic esophageal carcinoma.
