Evaluation of ventricular myocardial function in systemic sclerosis patients by echocardiography
10.3760/cma.j.issn.1007-7480.2011.05.010
- VernacularTitle:系统性硬化病患者心室功能评价:超声心动图研究
- Author:
Xiaoxiao GUO
;
Yongtai LIU
;
Zhuang TIA
;
Mengtao LI
;
Qian WANG
;
Quan FANG
;
Xiaofeng ZENG
- Publication Type:Journal Article
- Keywords:
Scleroderma,systemic;
Ultrasonography,Doppler;
Ventrieulary function,right
- From:
Chinese Journal of Rheumatology
2011;15(5):325-328
- CountryChina
- Language:Chinese
-
Abstract:
objecfive To analyze ventricular myocardial function in patients with systemic sclerosis (SSc).Methods Thirtv female SSc patients and fifteen age-and sex-comparable healthy subjects underwent standard echo and tissue Doppler imaging(TDI)examination.T-test and Pearson's analysis were used.Results Both left and right atrial and ventricular diameters,left ventricular eiection fraction and right ventricular fraction of area change were comparable between the two groups.Mitral and tricuspid inflow E/A ratio was almost the same in both groups,while systolic pulmoHary pressure was increased in SSc [(38±16)vs (23.9±4.8)mm Hg,P=0.008].TDI detected impaired right ventricular myocardial function in SSc:eartydiastolic peak velocity Em [(10.7±4.8)vs(15.0±2.1)cm/s,P=0.01],peak systolic strain[(-16.3±3.9)%vs (-20.9±2.0)%,P=0.001]and strain rate[(-1.4±0.4) vs(-2.4±0.5)/s,P<0.01] were reduced significantly.Left ventricular myocardial function was not impaired in SSc patients.Conclusion TDI iS a valuable noninvasive tool for early detecting of ventricular myocardial involvement caused by SSc.