Influence of atrial fibrillation type on plasma brain natriuretic peptide level in male patients

VernacularTitle:男性心房颤动类型对血浆脑钠肽水平的影响
Author: Licheng YU ; Geng LIU ; Jing YAO
Publication Type:Journal Article
Keywords: Atrial fibrillation; Brain natriuretic peptide; Arrhythmia
From: Clinical Medicine of China 2011;27(5):464-466
CountryChina
Language:Chinese
Abstract: Objective To explore the effect of different type of atrial fibrillation(AF) on plasma brain natriuretic peptide(BNP) level in male patients.Methods Fifty-eight hospitalized male patients with AF were enrolled,including 35 cases with paroxysmal AF,14 cases with persistent AF,and 9 cases with permanent AF.All subjects had the examination of echocardiography/electrocardiogram within 24 h after admission.Venous blood sample were collected in a quiet prostration state on the next early morning for BNP detection.The plasma BNP level was determined by radioimmunology-assay(RIA).Results The average level of plasma BNP in male patients with permanent AF(2343.25 ± 820.24)μg/L was significantly higher than those with persistent AF([576.43 ± 223.07]μg/L,t=8.74,P＜0.001) and paroxysmal AF([632.74 ± 103.93]μg/L,t=8.73,P＜0.001),but there was no significant difference between the last two groups(t=0.59,P＞0.05).Conclusion BNP is a sensitive indicator of early heart function impairment related with AF,particularly elevates in male patients with permanent AF.