Comparison of two in vitro gonadotrophin priming protocols in maturation treatment of patients with polycystic ovary syndrome
10.3760/cma.j.issn.1008-1372.2011.04.007
- VernacularTitle:两种激素启动方案对多囊卵巢综合征患者行卵母细胞体外成熟周期治疗效果的比较
- Author:
Fei GONG
;
Shuoping ZHANG
;
Sufen CAI
;
Guangxiu LU
- Publication Type:Journal Article
- Keywords:
Follicle stimulating hormone/AD;
Chorionic gonadotropin/AD;
Polycystic ovary syndrome/DT;
Fertilization in vitro
- From:
Journal of Chinese Physician
2011;13(4):454-457
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the therapeutic effect of two Methodsof in vitro oocyte maturation (IVM) technology with polycystic ovary syndrome (PCOS) patients in infertility treatment.MethodsRetrospective analysis was performed on patients with PCOS infertility who were stimulated with two different kinds of stimulating method of the IVM cycle in our center during April 2010 and August 2010.There were 20 patients in the temporary FSH stimulating group (group A) and 31 patients in the HCG stimulating group (group B).The number of oocytes maturation rate,fertilization rate,cleavage rate,excellent embryo rate,implantation rate,pregnancy rate per oocyte recycle,pregnancy rate per transfer and abortion rate of transfer were compared.ResultsThere was no significant difference between the two groups of age,duration of infertility,body mass index,based sex hormone levels by t test(P＞0.05).There was no significant difference between the two groups of the number of oocytes retrieved,oocyte maturation rate,cleavage rate,and abortion rate of transfer(P＞0.05).In group B,the fertilization rate was 80.3%,good-quality-embryo rate was 49.8%,implantation rate was 31.5%,pregnancy rate per oocyte recycle was 54.8%,which was significantly higher than in group A (73.9%,35.4%,12.5% and 25.0%,respectively).ConclusionsIf IVM was used to treat PCOS patients with infertility,HCG stimulating will be better than FSH stimulating,and it could result in a higher clinical pregnancy rate.
