Study the relationship between the imaging patterns of microvasculature change and histological diagnosis

Qiang Wang; Weiping Deng; Gongli Yang; Shu Jin; Weiguo Zhang; Qiang Tong

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Study the relationship between the imaging patterns of microvasculature change and histological diagnosis

VernacularTitle:食管病变上皮乳头内毛细血管袢的形态与病理组织的关系探讨
Author: Qiang WANG ; Weiping DENG ; Gongli YANG ; Shu JIN ; Weiguo ZHANG ; Qiang TONG
Publication Type:Journal Article
Keywords: Esophageal diseases/PA/DI; Mucous membrane/PA; Capillaries/PA; Endoscopy
From: Journal of Chinese Physician 2011;13(4):471-473
CountryChina
Language:Chinese
Abstract: Objective To study the relationship between the imaging patterns of microvasculature change and histological diagnosis.MethodsOne hundred and thirty-seven patients with esophageal mucosa roughness,erosion,plaque,abnormal color and indentation in conventional endoscopy and thirty healthy volunteers were enrolled in this study.The magnifying endoscopy images were graded as four patterns by intraepithelial papillary capillary loop(IPCL) changes by NBI .The biopsies underwent pathologic evaluation.The imaging patterns of endoscopy and histological diagnosis were compared and statistically analyzed.Results137 patients were diagnosed by narrow-band imaging system with magnifying endoscopy combined miniprobe sonography.Among these patients,27 cases were pathologically diagnosed as squamous cancer including 15 cases of early esophageal cancer,21 cases were high grade intraepithelial neoplasia,23 cases were low grade intraepithelial neoplasia,66 cases were chronic inflammation.100% esophageal carcinoma and high grade intraepithelial neoplasia were Ⅳ,Ⅲ type IPCL,56.52% low grade intraepithelial neoplasia was Ⅲ type IPCL,43.48% wasⅡtype IPCL,90.91% esophagitis wasⅡtype IPCL.100% esophageal normal mucosa wasⅠtype IPCL.The difference was significant among esophageal carcinoma,high grade intraepithelial neoplasia and esophagitis,esophageal normal mucosa (P＜0.05).ConclusionsThe imaging patterns of microvasculature change under NBI magnifying endoscopy were crucial in the diagnosis and identification of benign and malignant of esophageal disease.