Cell proliferation marker Ki-67 and breast cancer
10.3760/cma.j.issn.1673-422X.2011.05.014
- VernacularTitle:细胞增殖标志物Ki-67与乳腺癌
- Author:
Ming JIA
;
Bofei HU
;
Suju WEI
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Ki-67 antigen;
Prognosis
- From:
Journal of International Oncology
2011;38(5):364-366
- CountryChina
- Language:Chinese
-
Abstract:
Molecular markers have been widely used in the treatment of breast cancer. Cell proliferation markers Ki-67 antigen representing breast neoplasms proliferative activity is associated with clinic pathological features and prognosis and has an important predictive value in assessing the effect of neoadjuvant chemotherapy and endocrine therapy. High expression of Ki-67 is a bad prognostic factor of breast cancer, which is highly related to tumor progression, metastasis and prognosis.